sGC Pathway

Soluble Guanylate Cyclase Stimulators and Activators

Chapter in Handbook of Experimental Pharmacology (2019)

Peter Sandner, Daniel P. Zimmer, G. Todd Milne, Markus Follmann, Adrian Hobbs, Johannes-Peter Stasch

Co-authored by scientists from Cyclerion and Bayer, this review summarizes preclinical data supporting therapeutic opportunities for sGC modulators, both “activators” and “stimulators.”

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